• It depends of the platform you're targeting (mobile, consoles / PC ?).

• It depends of the aspect ratio you want (16/9, 4/3, or more exotic ones)

• It depends of the look you want (low fidelity / low res or high-res like fighting games)

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Overall, today most screens aspect ratios are 16/9 or 16/10.

The standard screen resolutions are 720p (1280x720) or 1080p (1920x1080).

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So let's say you want your pixel art scale 2:1

Then your target 1080p.

Just take the resolution and divide by 2. Examples :

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Pixel art scale 2:1 on 1080p

960x540

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Pixel art scale 3:1 on 1080p

640x360

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Pixel art scale 4:1 on 1080p

480x240

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