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You need to go to "Settings" --> "Developer Options" --> "Select debug app" on you Actual Device.
After clicking on "Select debug app", there will be a list of your installed apps, Select the app you want to run.
That is it you will not see the "Waiting For Debugger" message any more.
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you need to enable Debug Mode and then resign the app.
this link explains how:
https://www.evilsocket.net/2017/04/27/Android-Applications-Reversing-101/#Debugging
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Go to Run menu ====> click on Edit Configurations ====> Micellaneous and finaly uncheck the option Skip installation if APK has not changed